AzlB

• Description: transcriptional repressor of the azlB-azlC-azlD-brnQ-yrdK operon
  
  

Gene name	azlB
Synonyms	yrdG
Essential	no
Product	transcriptional repressor
Function	regulation of branched-chain amino acid transport
MW, pI	17 kDa, 4.867
Gene length, protein length	471 bp, 157 aa
Immediate neighbours	azlC, yrdF
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

biosynthesis/ acquisition of amino acids, utilization of amino acids, transcription factors and their control, membrane proteins

This gene is a member of the following regulons

AzlB regulon

The AzlB regulon:

• azlB-azlC-azlD-brnQ-yrdK

The gene

Basic information

• Locus tag: BSU26720

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O07920

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: azlB-azlC-azlD-brnQ-yrdK PubMed

• Sigma factor:

• Regulation: repressed by AzlB PubMed

• Regulatory mechanism: AzlB: transcriptional repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

B R Belitsky, M C Gustafsson, A L Sonenshein, C Von Wachenfeldt
An lrp-like gene of Bacillus subtilis involved in branched-chain amino acid transport.
J Bacteriol: 1997, 179(17);5448-57
[PubMed:9287000] [WorldCat.org] [DOI] (P p)