EpsE

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  • Description: inhibitor of motility and glycosyltransferase required for EPS biosynthesis

Gene name epsE
Synonyms yveO
Essential no
Product glycosyltransferase, inhibitor of motility
Function biofilm formation
Regulation of this protein in SubtiPathways:
Biofilm
MW, pI 32 kDa, 9.804
Gene length, protein length 834 bp, 278 aa
Immediate neighbours epsF, epsD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YveO context.gif
This image was kindly provided by SubtiList







Categories containing this gene/protein

motility and chemotaxis, biofilm formation, membrane proteins

This gene is a member of the following regulons

EAR riboswitch, SinR regulon

The gene

Basic information

  • Locus tag: BSU34330

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • arrests flagellar rotation in a manner similar to that of a clutch, by disengaging motor force-generating elements in cells embedded in the biofilm matrix PubMed
    • biosynthesis of extracellular polysaccharides 21170308 PubMed
  • Protein family: glycosyltransferase 2 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane, forms spots at flagellar basal bodies PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Massimiliano Marvasi, Pieter T Visscher, Lilliam Casillas Martinez
Exopolymeric substances (EPS) from Bacillus subtilis: polymers and genes encoding their synthesis.
FEMS Microbiol Lett: 2010, 313(1);1-9
[PubMed:20735481] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed