CopZ

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  • Description: copper transport protein, metallochaperone

Gene name copZ
Synonyms yvgY
Essential no
Product copper transport protein, metallochaperone
Function resistance to copper
MW, pI 7 kDa, 4.162
Gene length, protein length 207 bp, 69 aa
Immediate neighbours copA, csoR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YvgY context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

transporters/ other, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), resistance against toxic metals

This gene is a member of the following regulons

CsoR regulon

The gene

Basic information

  • Locus tag: BSU33510

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): carries a tetranuclear Cu(I) cluster (as [Cu4(S-Cys)4(N-His)2] cluster) PubMed
  • Effectors of protein activity:
  • Interactions: CopA-CopZ, for the transfer of the Cu(I) cluster PubMed
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Your additional remarks

References