DsdA

• Description: D-serine deaminase
  
  

Gene name	dsdA
Synonyms	yqjR
Essential	no
Product	D-serine deaminase
Function	unknown
Metabolic function and regulation of this protein in SubtiPathways: Coenzyme A
MW, pI	49 kDa, 5.55
Gene length, protein length	1344 bp, 448 aa
Immediate neighbours	coaA, yqjQ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU23770

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

poorly characterized/ putative enzymes

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: D-serine = pyruvate + NH₃ (according to Swiss-Prot)

• Protein family: DsdA subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P54555

• KEGG entry: [3]

• E.C. number: 4.3.1.18

Expression and regulation

• Operon: yqjP-yqjQ-dsdA-coaA-yqjT (according to DBTBS)

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

C Parsot
Evolution of biosynthetic pathways: a common ancestor for threonine synthase, threonine dehydratase and D-serine dehydratase.
EMBO J: 1986, 5(11);3013-9
[PubMed:3098560] [WorldCat.org] [DOI] (P p)