TenI

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  • Description: transcriptional activator of extracellular enzyme genes

Gene name tenI
Synonyms
Essential no
Product transcriptional activator
Function regulation of extracellular enzyme genes
Metabolic function and regulation of this protein in SubtiPathways:
Thiamin
MW, pI 22 kDa, 8.132
Gene length, protein length 615 bp, 205 aa
Immediate neighbours tenA, thiO
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
TenI context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU11660

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: TMP-PPase family (according to Swiss-Prot)
  • Paralogous protein(s): ThiE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Angela V Toms, Amy L Haas, Joo-Heon Park, Tadhg P Begley, Steven E Ealick
Structural characterization of the regulatory proteins TenA and TenI from Bacillus subtilis and identification of TenA as a thiaminase II.
Biochemistry: 2005, 44(7);2319-29
[PubMed:15709744] [WorldCat.org] [DOI] (P p)

A S Pang, S Nathoo, S L Wong
Cloning and characterization of a pair of novel genes that regulate production of extracellular enzymes in Bacillus subtilis.
J Bacteriol: 1991, 173(1);46-54
[PubMed:1898926] [WorldCat.org] [DOI] (P p)