NrnB

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  • Description: oligoribonuclease (nano-RNase)

Gene name nrnB
Synonyms yngD
Essential no
Product nano-RNase B
Function degradation of RNA oligonucleotides
MW, pI 46 kDa, 5.026
Gene length, protein length 1197 bp, 399 aa
Immediate neighbours yngC, yngE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YngD context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU18200

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: degradation of RNA oligonucleotides PubMed
  • Protein family: DHH/DHHA1 protein family of phosphoesterases PubMed
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Ming Fang, Wencke-Maria Zeisberg, Ciaran Condon, Vasily Ogryzko, Antoine Danchin, Undine Mechold
Degradation of nanoRNA is performed by multiple redundant RNases in Bacillus subtilis.
Nucleic Acids Res: 2009, 37(15);5114-25
[PubMed:19553197] [WorldCat.org] [DOI] (I p)