CtaA

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  • Description: heme A synthase

Gene name ctaA
Synonyms
Essential no
Product heme A synthase
Function heme biosynthesis
Gene expression levels in SubtiExpress: ctaA
MW, pI 33 kDa, 9.644
Gene length, protein length 918 bp, 306 aa
Immediate neighbours pycA, ctaB
Sequences Protein DNA DNA_with_flanks
Genetic context
CtaA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CtaA expression.png















Categories containing this gene/protein

biosynthesis of cofactors, sporulation proteins, membrane proteins

This gene is a member of the following regulons

ResD regulon, SigE regulon

The gene

Basic information

  • Locus tag: BSU14870

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: COX15/ctaA family, Type 1 subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): heme B
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under anaerobic conditions (ResD) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Lars Hederstedt
Heme A biosynthesis.
Biochim Biophys Acta: 2012, 1817(6);920-7
[PubMed:22484221] [WorldCat.org] [DOI] (P p)

Original publications