MtnB

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  • Description: methylthioribulose-1-phosphate dehydratase

Gene name mtnB
Synonyms ykrY
Essential no
Product methylthioribulose-1-phosphate dehydratase
Function methionine salvage
Gene expression levels in SubtiExpress: mtnB
Metabolic function and regulation of this protein in SubtiPathways:
Cys, Met & Sulfate assimilation
MW, pI 23 kDa, 5.686
Gene length, protein length 627 bp, 209 aa
Immediate neighbours mtnX, mtnD
Sequences Protein DNA DNA_with_flanks
Genetic context
YkrY context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MtnB expression.png




























Categories containing this gene/protein

biosynthesis/ acquisition of amino acids

This gene is a member of the following regulons

S-box

The gene

Basic information

  • Locus tag: BSU13610

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: S-methyl-5-thio-D-ribulose 1-phosphate = 5-(methylthio)-2,3-dioxopentyl phosphate + H2O (according to Swiss-Prot)
  • Protein family: MtnB subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism: S-box: transcription termination/ antitermination, the S-box riboswitch binds S-adenosylmethionine resulting in termination PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References