DppE

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Gene name dppE
Synonyms dciAE
Essential no
Product dipeptide ABC transporter (dipeptide-binding protein)
Function uptake of dipeptides
Gene expression levels in SubtiExpress: dppE
Interactions involving this protein in SubtInteract: DppE
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 62 kDa, 5.523
Gene length, protein length 1647 bp, 549 aa
Immediate neighbours dppD, ykfA
Sequences Protein DNA DNA_with_flanks
Genetic context
DppE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DppE expression.png


























Categories containing this gene/protein

ABC transporters, utilization of nitrogen sources other than amino acids, membrane proteins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU12960

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial solute-binding protein 5 family (according to Swiss-Prot)
  • Paralogous protein(s): OppA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: GP1110 (spc), available in Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References