LspA

From SubtiWiki
Revision as of 12:47, 13 May 2013 by 134.76.70.252 (talk)
Jump to: navigation, search
  • Description: signal peptidase II

Gene name lspA
Synonyms lsp
Essential no
Product signal peptidase II
Function protein secretion
Gene expression levels in SubtiExpress: lspA
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 17 kDa, 9.133
Gene length, protein length 462 bp, 154 aa
Immediate neighbours ylyA, ylyB
Sequences Protein DNA Advanced_DNA
Genetic context
LspA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LspA expression.png
























Categories containing this gene/protein

protein secretion, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU15450

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Release of signal peptides from bacterial membrane prolipoproteins (according to Swiss-Prot)
  • Protein family: peptidase A8 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

J Bengtsson, H Tjalsma, C Rivolta, L Hederstedt
Subunit II of Bacillus subtilis cytochrome c oxidase is a lipoprotein.
J Bacteriol: 1999, 181(2);685-8
[PubMed:9882689] [WorldCat.org] [DOI] (P p)