DeoR

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  • Description: transcriptional repressor of the dra-nupC-pdp operon

Gene name deoR
Synonyms yxxC
Essential no
Product transcriptional repressor
Function regulation of deoxyribonucleotide utilization
Gene expression levels in SubtiExpress: deoR
Metabolic function and regulation of this protein in SubtiPathways:
Nucleoside catabolism, Nucleotides (regulation)
MW, pI 35 kDa, 6
Gene length, protein length 939 bp, 313 aa
Immediate neighbours dra, yxxB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
DeoR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
DeoR expression.png




























Categories containing this gene/protein

utilization of nucleotides, transcription factors and their control

This gene is a member of the following regulons

The DeoR regulon:

The gene

Basic information

  • Locus tag: BSU39430

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: transcription repression of the dra-nupC-pdp operon
  • Protein family: sorC transcriptional regulatory family (according to Swiss-Prot) DeoR family of transcription repressors
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

X Zeng, H H Saxild, R L Switzer
Purification and characterization of the DeoR repressor of Bacillus subtilis.
J Bacteriol: 2000, 182(7);1916-22
[PubMed:10714997] [WorldCat.org] [DOI] (P p)

X Zeng, H H Saxild
Identification and characterization of a DeoR-specific operator sequence essential for induction of dra-nupC-pdp operon expression in Bacillus subtilis.
J Bacteriol: 1999, 181(6);1719-27
[PubMed:10074062] [WorldCat.org] [DOI] (P p)

H H Saxild, L N Andersen, K Hammer
Dra-nupC-pdp operon of Bacillus subtilis: nucleotide sequence, induction by deoxyribonucleosides, and transcriptional regulation by the deoR-encoded DeoR repressor protein.
J Bacteriol: 1996, 178(2);424-34
[PubMed:8550462] [WorldCat.org] [DOI] (P p)