YrhJ

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Revision as of 13:59, 17 May 2011 by Umaeder (talk | contribs) (Expression and regulation)
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Gene name yrhJ
Synonyms cypE
Essential no
Product NADPH-cytochrome P450 reductase
Function fatty acid metabolism
MW, pI 118 kDa, 6.017
Gene length, protein length 3162 bp, 1054 aa
Immediate neighbours yrhK, fatR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YrhJ context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

electron transport/ other, lipid metabolism/ other, cell envelope stress proteins (controlled by SigM, W, X, Y), membrane proteins

This gene is a member of the following regulons

FatR regulon, SigM regulon

The gene

Basic information

  • Locus tag: BSU27160

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • hydroxylates medium-chain fatty acids in subterminal positions PubMed
  • Protein family:
  • Paralogous protein(s): YetO

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure: 2X7Y (from Bacillus megaterium; 67% identity, 88% similarity)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • induced by unsaturated fatty acids (FatR) PubMed
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References