MifM

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  • Description: ribosome-nascent chain sensor of membrane protein biogenesis

Gene name mifM
Synonyms yqzJ
Essential no
Product sensor of SpoIIIJ activity
Function control of yidC2 translation
Gene expression levels in SubtiExpress: mifM
MW, pI 11 kDa, 5.829
Gene length, protein length 285 bp, 95 aa
Immediate neighbours polY1, yidC2
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YqzJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MifM expression.png















Categories containing this gene/protein

translation, membrane proteins

This gene is a member of the following regulons

The MifM regulon: yidC2

The gene

Basic information

  • Locus tag: BSU23880

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: acts as a kind of "leader peptide" that does or does not allow translation through a hairpin structure in the yidC2 mRNA PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
    • the C-terminus of MifM interacts with the ribosomal polypeptide exit tunnel PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References