Maf

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  • Description: cell division inhibitor in competent cells, blocks septation during the escape from competence, required for the stability of ComGA

Gene name maf
Synonyms
Essential no
Product cell division inhibitor
Function cell division control
Interactions involving this protein in SubtInteract: Maf
MW, pI 21 kDa, 5.711
Gene length, protein length 567 bp, 189 aa
Immediate neighbours radC, spoIIB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Maf context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Maf expression.png
























Categories containing this gene/protein

cell division

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU28050

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: maf family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): binds phosphorylated compounds (UTP, IMP, IDP, GDP and others) in in vitro experiments
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
    • expressed when cells enter the compentent state (ComK) PubMed
    • expression is reduced in a SigV mutant PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

PubMed

Original publications

Additional publications: PubMed