GltC
- Synonyms:
- Description: Transcriptional activator of the gltAB operon. Activates expression of the operon in the absence of arginine.
Contents
The gene
Basic information
- Coordinates:
- Gene length:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry:[2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activation of the gltAB operon
- Protein family: LysR-type transcription regulator
- Paralogous protein(s): none, but there are 19 members of the LysR family in B. subtilis
Extended information on the protein
- Kinetic information:
- Domains: DNA-binding helix-turn-helix motif: AA 18 ... 37
- Modification:
- Effectors of protein activity: 2-oxoglutarate
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P20668
- KEGG entry: KEGG
Additional information
Expression and regulation
- Operon: gltC
- Sigma factor: SigA
- Regulation: autoregulation by GltC
- Regulatory mechanism: autorepression
- Database entries: DBTBS
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- Antibody: available in Stülke lab
Labs working on this gene/protein
Linc Sonenshein, Tufts University, Boston, MA, USA [3]
Jörg Stülke, University of Göttingen, Germany [4]
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. [5]