Difference between revisions of "MenB"

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=The gene=
 
=The gene=

Revision as of 15:29, 22 June 2009

  • Description: naphthoate synthase

Gene name menB
Synonyms
Essential yes PubMed
Product naphthoate synthase
Function biosynthesis of menaquinone
Metabolic function and regulation of this protein in SubtiPathways:
Menaquinone
MW, pI 29 kDa, 5.343
Gene length, protein length 813 bp, 271 aa
Immediate neighbours menE, ytxM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
MenB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU30800

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: o-succinylbenzoyl-CoA = CoA + 1,4-dihydroxy-2-naphthoate (according to Swiss-Prot)
  • Protein family: enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

J R Driscoll, H W Taber
Sequence organization and regulation of the Bacillus subtilis menBE operon.
J Bacteriol: 1992, 174(15);5063-71
[PubMed:1629163] [WorldCat.org] [DOI] (P p)