Difference between revisions of "AraN"

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* '''Regulation:''' repressed by glucose ([[CcpA]])
 
* '''Regulation:''' repressed by glucose ([[CcpA]])
 +
** repressed in the absence of arabinose ([[AraR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed]
  
 
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression  
 
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression  
 +
** [[AraR]]:  transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/10417639 PubMed]
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 11:45, 11 June 2009

  • Description: L-arabinose transport (sugar-binding protein)

Gene name araN
Synonyms yseC
Essential no
Product L-arabinose transport (sugar-binding protein))
Function uptake of arabinose
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 48 kDa, 8.555
Gene length, protein length 1299 bp, 433 aa
Immediate neighbours araP, araM
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AraN context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU28750

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial solute-binding protein 1 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA)
    • repressed in the absence of arabinose (AraR) PubMed
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Inácio JM, Costa C, de Sá-Nogueira I. (2003) Distinct molecular mechanisms involved in carbon catabolite repression of the arabinose regulon in Bacillus subtilis. Microbiology. Sep;149(Pt 9): 2345-55. [http://www.ncbi.nlm.nih.gov/sites/entrez/12949161 PubMed
  2. Sa-Nogueira I.M.G., Nogueira T.V., Soares S., de Lencastre H. (1997) The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression. Microbiology. Mar;143(Pt 3): 957-69. PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed