Difference between revisions of "AraM"

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=== Basic information ===
 
=== Basic information ===
  
* '''Locus tag:'''
+
* '''Locus tag:''' BSU28760
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94527 P94527]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94527 P94527]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU28760 BSU28760]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU28760]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.261 1.1.1.261]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.261 1.1.1.261]

Revision as of 13:34, 3 June 2009

  • Description: glycerol-1-phosphate dehydrogenase, L-arabinose operon

Gene name araM
Synonyms yseB
Essential no
Product glycerol-1-phosphate dehydrogenase
Function biosynthesis of phosphoglycerolipids
MW, pI 42 kDa, 5.628
Gene length, protein length 1182 bp, 394 aa
Immediate neighbours araN, araL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
AraM context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU28760

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: sn-glycerol-1-phosphate + NAD(P)+ = glycerone phosphate + NAD(P)H (according to Swiss-Prot)
  • Protein family: glycerol-1-phosphate dehydrogenase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: repressed by glucose (CcpA)
  • Regulatory mechanism: CcpA: transcription repression
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Inácio JM, Costa C, de Sá-Nogueira I. (2003) Distinct molecular mechanisms involved in carbon catabolite repression of the arabinose regulon in Bacillus subtilis. Microbiology. Sep;149(Pt 9): 2345-55. PubMed
  2. Sa-Nogueira I.M.G., Nogueira T.V., Soares S., de Lencastre H. (1997) The Bacillus subtilis L-arabinose (ara) operon: nucleotide sequence, genetic organization and expression. Microbiology. Mar;143(Pt 3): 957-69. PubMed
  3. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed