Difference between revisions of "ParC"

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=== Database entries ===
 
=== Database entries ===
  
* '''Structure:'''
+
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1WP5 1WP5] (C-terminal domain, Geobacillus stearothermophilus)
  
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/Q45066 Q45066]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/Q45066 Q45066]

Revision as of 22:17, 5 May 2009

  • Description: subunit of DNA topoisomerase IV

Gene name parC
Synonyms grlA
Essential yes PubMed
Product subunit of DNA topoisomerase IV
Function chromosome segregation and compaction
MW, pI 91 kDa, 6.307
Gene length, protein length 2418 bp, 806 aa
Immediate neighbours parE, ynfC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
ParC context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): GyrA

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot), Cytoplasm (Homogeneous) PubMed polar localization in actively growing cells PubMed

Database entries

  • Structure: 1WP5 (C-terminal domain, Geobacillus stearothermophilus)
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Meile et al. (2006) Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory Proteomics 6: 2135-2146. PubMed
  2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed