Difference between revisions of "PurR"

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(New page: * '''Description:''' write here <br/><br/> {| align="right" border="1" cellpadding="2" |- |style="background:#ABCDEF;" align="center"|'''Gene name''' |''purR'' |- |style="background:#ABC...)
 
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* '''Description:''' write here <br/><br/>
+
* '''Description:''' purine repressor<br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator
 
|style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || negative regulation of the purine operons (purEKBCLQFMNHD, purA)
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|style="background:#ABCDEF;" align="center"|'''Function''' || negative regulation of the purine operons (''[[purE| purEKBCLQFMNHD]]'', ''[[purA]]'')
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 5.771   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 31 kDa, 5.771   
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* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
  
* '''Effectors of protein activity:'''
+
* '''Effectors of protein activity:''' PRPP acts as inducer, binding results in release of PurR from the operator
  
* '''Interactions:'''
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* '''Interactions:''' [[PurR]]-[[Prs]]
  
 
* '''Localization:'''
 
* '''Localization:'''
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=== Additional information===
 
=== Additional information===
 +
 +
requires [[YabJ]] for ''in vivo'' activity
  
 
=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:'''  
+
* '''Operon:''' ''[[purR]]-[[yabJ]]''
  
 
* '''Sigma factor:'''  
 
* '''Sigma factor:'''  

Revision as of 14:09, 1 February 2009

  • Description: purine repressor

Gene name purR
Synonyms yabI
Essential
Product transcriptional regulator
Function negative regulation of the purine operons ( purEKBCLQFMNHD, purA)
MW, pI 31 kDa, 5.771
Gene length, protein length 855 bp, 285 aa
Immediate neighbours
Gene sequence (+200bp) Protein sequence
Genetic context
PurR context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: PRPP acts as inducer, binding results in release of PurR from the operator
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

requires YabJ for in vivo activity

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed