Difference between revisions of "FloT"
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* '''Additional information:''' | * '''Additional information:''' | ||
+ | ** number of protein molecules per cell (minimal medium with glucose and ammonium): 1215 {{PubMed|24696501}} | ||
+ | ** number of protein molecules per cell (complex medium with amino acids, without glucose): 236 {{PubMed|24696501}} | ||
=Biological materials = | =Biological materials = |
Revision as of 11:24, 17 April 2014
- Description: similar to flotillin 1, orchestration of physiological processes in lipid microdomains, involved in the control of membrane fluidity, confers (together with YuaF) resistance to cefuroxime
Gene name | floT |
Synonyms | yuaG, yuaH |
Essential | no |
Product | bacterial flotillin-like protein |
Function | involved in the control of membrane fluidity |
Gene expression levels in SubtiExpress: floT | |
Interactions involving this protein in SubtInteract: FloT | |
MW, pI | 55 kDa, 5.135 |
Gene length, protein length | 1527 bp, 509 aa |
Immediate neighbours | yuaI, yuaF |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
biofilm formation, membrane dynamics, membrane proteins sporulation/ other, cell envelope stress proteins (controlled by SigM, V, W, X, Y)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31010
Phenotypes of a mutant
- delayed onset of sporulation, reduced sporulation frequency
- defect in motility PubMed
- reduced protein secretion PubMed
- a floT floA double mutant does not induce KinC-dependent biofilm formation upon addition of surfactin PubMed
- a floT floA double mutant has a strong synthetic defect in motility, cell morphology, and transformation efficiency PubMed
- a floT floA double mutant has a sporulation defect, due to the lack of FtsH PubMed
Database entries
- BsubCyc: BSU31010
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU31010
- Structure:
- UniProt: O32076
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References