Difference between revisions of "PgdS"

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=References=
'''Additional publications:''' {{PubMed|23335395}}
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<pubmed>18957862 12644511, 15033535 23335395</pubmed>
<pubmed>18957862 12644511, 15033535 </pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:47, 4 December 2013

  • Description: gamma-DL-glutamyl hydrolase

Gene name pgdS
Synonyms ywtD
Essential no
Product gamma-DL-glutamyl hydrolase
Function polyglutamic acid degradation
Gene expression levels in SubtiExpress: pgdS
MW, pI 45 kDa, 8.52
Gene length, protein length 1239 bp, 413 aa
Immediate neighbours ywtE, capE
Sequences Protein DNA DNA_with_flanks
Genetic context
YwtD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PgdS expression.png















Categories containing this gene/protein

capsule biosynthesis and degradation

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

  • Locus tag: BSU35860

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: nlpC/p60 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Viola Scoffone, Daniele Dondi, Ginevra Biino, Giovanni Borghese, Dario Pasini, Alessandro Galizzi, Cinzia Calvio
Knockout of pgdS and ggt genes improves γ-PGA yield in B. subtilis.
Biotechnol Bioeng: 2013, 110(7);2006-12
[PubMed:23335395] [WorldCat.org] [DOI] (I p)

Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862] [WorldCat.org] [DOI] (I p)

Masakuni Serizawa, Hiroki Yamamoto, Hirotake Yamaguchi, Yasutaro Fujita, Kazuo Kobayashi, Naotake Ogasawara, Junichi Sekiguchi
Systematic analysis of SigD-regulated genes in Bacillus subtilis by DNA microarray and Northern blotting analyses.
Gene: 2004, 329;125-36
[PubMed:15033535] [WorldCat.org] [DOI] (P p)

Takao Suzuki, Yasutaka Tahara
Characterization of the Bacillus subtilis ywtD gene, whose product is involved in gamma-polyglutamic acid degradation.
J Bacteriol: 2003, 185(7);2379-82
[PubMed:12644511] [WorldCat.org] [DOI] (P p)