Difference between revisions of "PksA"
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| − | * '''Description:''' transcriptional regulator of the polyketide synthase operon <br/><br/> | + | * '''Description:''' transcriptional regulator ([[TetR family]]) of the polyketide synthase operon <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator (TetR family) | + | |style="background:#ABCDEF;" align="center"| '''Product''' || transcriptional regulator ([[TetR family]]) |
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of polyketide synthesis | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of polyketide synthesis | ||
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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<br/><br/> | <br/><br/> | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| − | * '''Protein family:''' | + | * '''Protein family:''' [[TetR family]] |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pksA_1781906_1782523_1 pksA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=pksA_1781906_1782523_1 pksA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
| − | + | ==Reviews== | |
| + | <pubmed>24006471 </pubmed> | ||
| + | ==Original publications== | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:30, 6 September 2013
- Description: transcriptional regulator (TetR family) of the polyketide synthase operon
| Gene name | pksA |
| Synonyms | |
| Essential | no |
| Product | transcriptional regulator (TetR family) |
| Function | regulation of polyketide synthesis |
| Gene expression levels in SubtiExpress: pksA | |
| MW, pI | 23 kDa, 6.436 |
| Gene length, protein length | 615 bp, 205 aa |
| Immediate neighbours | ymcC, pksB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, transcription factors and their control, biosynthesis of antibacterial compounds
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU17080
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: TetR family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34381
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Leslie Cuthbertson, Justin R Nodwell
The TetR family of regulators.
Microbiol Mol Biol Rev: 2013, 77(3);440-75
[PubMed:24006471]
[WorldCat.org]
[DOI]
(I p)
