ZapA

• Description: positive modulator of FtsZ Z ring assembly and stability
  
  

Gene name	zapA
Synonyms	yshA
Essential	no
Product	Z-ring-associated protein
Function	control of Z-ring formation
Gene expression levels in SubtiExpress: zapA
Interactions involving this protein in SubtInteract: ZapA
MW, pI	9 kDa, 7.17
Gene length, protein length	255 bp, 85 aa
Immediate neighbours	yshB, rnhC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell division, membrane proteins

The gene

Basic information

• Locus tag: BSU28610

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: Type 2 subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • forms a dimer through its extensive coiled-coil region, FtsZ-ZapA PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P94542

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: zapA-yshB PubMed

• Expression browser: zapA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Marc Bramkamp, Suey van Baarle
Division site selection in rod-shaped bacteria.
Curr Opin Microbiol: 2009, 12(6);683-8
[PubMed:19884039] [WorldCat.org] [DOI] (I p)

David W Adams, Jeff Errington
Bacterial cell division: assembly, maintenance and disassembly of the Z ring.
Nat Rev Microbiol: 2009, 7(9);642-53
[PubMed:19680248] [WorldCat.org] [DOI] (I p)