Difference between revisions of "ComGB"

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Revision as of 13:54, 16 May 2013

  • Description: polytopic membrane protein , DNA transport machinery

Gene name comGB
Synonyms
Essential no
Product DNA transport machinery
Function genetic competence, DNA uptake
Gene expression levels in SubtiExpress: comGB
Interactions involving this protein in SubtInteract: ComGB
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 36 kDa, 8.654
Gene length, protein length 969 bp, 323 aa
Immediate neighbours comGC, comGA
Sequences Protein DNA DNA_with_flanks
Genetic context
ComGB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComGB expression.png
























Categories containing this gene/protein

genetic competence, membrane proteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU24720

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: GSP F family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Inês Chen, David Dubnau
DNA uptake during bacterial transformation.
Nat Rev Microbiol: 2004, 2(3);241-9
[PubMed:15083159] [WorldCat.org] [DOI] (P p)

Original publications