Difference between revisions of "SndA"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytnM]]'', ''[[ribR]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ytnM]]'', ''[[ribR]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29290 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29290 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29290 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU29290 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU29290 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU29290 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ytnL_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ytnL_context.gif]]

Revision as of 10:59, 14 May 2013

  • Description: unknown

Gene name ytnL
Synonyms hipO
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: ytnL
Metabolic function and regulation of this protein in SubtiPathways:
Riboflavin / FAD
MW, pI 45 kDa, 5.545
Gene length, protein length 1248 bp, 416 aa
Immediate neighbours ytnM, ribR
Sequences Protein DNA DNA_with_flanks
Genetic context
YtnL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YtnL expression.png















Categories containing this gene/protein

proteins of unknown function

This gene is a member of the following regulons

CymR regulon, YtlI regulon, Efp-dependent proteins

The gene

Basic information

  • Locus tag: BSU29290

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase M20 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

The gene was annotated in KEGG and MetaCyc as hippurate hydrolase EC 3.5.1.32. In Swiss-Prot it is marked as “uncharacterized hydrolase”. No literature/experimental evidence supporting ththeannotation was removed as of November 2009. PubMed

Expression and regulation

  • Regulation:
    • repressed in the presence of cysteine (CymR) PubMed
  • Additional information:
    • translation is likely to require Efp due to the presence of several consecutive proline residues PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Pierre Burguière, Juliette Fert, Isabelle Guillouard, Sandrine Auger, Antoine Danchin, Isabelle Martin-Verstraete
Regulation of the Bacillus subtilis ytmI operon, involved in sulfur metabolism.
J Bacteriol: 2005, 187(17);6019-30
[PubMed:16109943] [WorldCat.org] [DOI] (P p)

Irina M Solovieva, Rimma A Kreneva, Lubov Errais Lopes, Daniel A Perumov
The riboflavin kinase encoding gene ribR of Bacillus subtilis is a part of a 10 kb operon, which is negatively regulated by the yrzC gene product.
FEMS Microbiol Lett: 2005, 243(1);51-8
[PubMed:15668000] [WorldCat.org] [DOI] (P p)