Difference between revisions of "YydF"

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* '''Modification:'''
 
* '''Modification:'''
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** modified by [[YydG]] {{PubMed|23106164}}
  
 
* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
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** [[YydF]]-[[YydG]] {{PubMed|23106164}}
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** [[YydF]]-[[YydH]] {{PubMed|23106164}}
  
 
* '''[[Localization]]:'''
 
* '''[[Localization]]:'''
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** extracellular (processing requires [[YydH]])
  
 
=== Database entries ===
 
=== Database entries ===
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=References=
 
=References=
 +
==Reviews==
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<pubmed> 23106164</pubmed>
 +
==Original publications==
 
  <big>''Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J''  </big>
 
  <big>''Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J''  </big>
 
  <big>'''RNA processing in ''Bacillus subtilis'': identification of targets of the essential RNase Y.''' </big>
 
  <big>'''RNA processing in ''Bacillus subtilis'': identification of targets of the essential RNase Y.''' </big>

Revision as of 13:35, 31 October 2012

  • Description: secreted peptide, controls LiaR-LiaS activity

Gene name yydF
Synonyms
Essential no
Product secreted peptide
Function control of LiaR-LiaS activity
Gene expression levels in SubtiExpress: yydF
MW, pI 5 kDa, 9.567
Gene length, protein length 147 bp, 49 aa
Immediate neighbours yydG, fbp
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YydF context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
500px















Categories containing this gene/protein

transcription factors and their control

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

  • Locus tag: BSU40180

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • activated after transition to stationary phase(AbrB) PubMed
  • Regulatory mechanism:
  • Additional information:
    • the mRNA is very stable (half-life > 15 min) PubMed
    • the yydF portion of the mRNA belongs to the most stable mRNAs in B. subtilis PubMed
    • the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Susanne Gebhard
ABC transporters of antimicrobial peptides in Firmicutes bacteria - phylogeny, function and regulation.
Mol Microbiol: 2012, 86(6);1295-317
[PubMed:23106164] [WorldCat.org] [DOI] (I p)

Original publications

Lehnik-Habrink M, Schaffer M, Mäder U, Diethmaier C, Herzberg C, Stülke J  
RNA processing in Bacillus subtilis: identification of targets of the essential RNase Y. 
Mol Microbiol. 2011 81(6): 1459-1473. 
PubMed:21815947