Difference between revisions of "NdoA"

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Revision as of 14:43, 18 April 2012

  • Description: RNase EndoA, MazF family toxin, UACAU-specific mRNA interferase

Gene name ndoA
Synonyms ydcE
Essential no
Product mRNA interferase
Function unknown
Interactions involving this protein in SubtInteract: NdoA
MW, pI 12 kDa, 4.892
Gene length, protein length 348 bp, 116 aa
Immediate neighbours ndoAI, rsbR
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YdcE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NdoA expression.png
























Categories containing this gene/protein

Rnases, toxins, antitoxins and immunity against toxins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU04660

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: specifically cleaves a five-base sequence, UACAU PubMed
  • Protein family: pemK family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: the activity is inhibited by the interaction with NdoAI PubMed

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References