Difference between revisions of "PbpE"
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* '''Regulation:''' | * '''Regulation:''' | ||
− | ** repressed during logrithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592498 PubMed], probably indirect regulation by AbrB {{PubMed|20817675}} | + | ** repressed during logrithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592498 PubMed], probably indirect regulation by [[AbrB]] {{PubMed|20817675}} |
** induced by cell wall stress ([[SigW]]) {{PubMed|8491712,12207695}} | ** induced by cell wall stress ([[SigW]]) {{PubMed|8491712,12207695}} | ||
Revision as of 17:11, 30 May 2011
- Description: penicillin-binding protein PBP 4* (spore cortex)
Gene name | pbpE |
Synonyms | |
Essential | no |
Product | penicillin-binding protein PBP 4* (spore cortex) |
Function | endopeptidase |
MW, pI | 51 kDa, 4.835 |
Gene length, protein length | 1353 bp, 451 aa |
Immediate neighbours | racX, sacB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
cell wall synthesis, cell wall degradation/ turnover, cell envelope stress proteins (controlled by SigM, W, X, Y)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU34440
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: beta-lactamase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: spore cortex
Database entries
- Structure:
- UniProt: P32959
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References