Difference between revisions of "SpoIISB"
| Line 45: | Line 45: | ||
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| + | * sporulation efficiency is reduced by four orders of magnitude {{PubMed|11371520}} | ||
=== Database entries === | === Database entries === | ||
| Line 79: | Line 80: | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| − | * '''Interactions:''' | + | * '''Interactions:''' [[SpoIISA]]-[[SpoIISB]] {{PubMed|21147767}} |
* '''Localization:''' | * '''Localization:''' | ||
| Line 85: | Line 86: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.pdb.org/pdb/explore/explore.do?structureId=3O6Q 3O6Q] (cytoplasmic fragment of [[SpoIISA]] (CSpoIISA) in complex with [[SpoIISB]]) {{PubMed|21147767}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/O34800 O34800] | * '''UniProt:''' [http://www.uniprot.org/uniprot/O34800 O34800] | ||
| Line 98: | Line 99: | ||
* '''Operon:''' | * '''Operon:''' | ||
| + | * ''[[spoIISA]]-[[spoIISB]]'' {{PubMed|11371520}} | ||
| + | * ''[[spoIISB]]'' {{PubMed|11371520}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| Line 127: | Line 130: | ||
=References= | =References= | ||
| − | <pubmed>18096016,, </pubmed> | + | <pubmed>18096016,11371520, 21147767</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 09:45, 15 December 2010
- Description: disruption blocks sporulation after septum formation
| Gene name | spoIISB |
| Synonyms | |
| Essential | no |
| Product | anti-toxin |
| Function | sporulation |
| MW, pI | 6 kDa, 10.794 |
| Gene length, protein length | 168 bp, 56 aa |
| Immediate neighbours | xlyA, spoIISA |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
sporulation/ other, toxins, antitoxins and immunity against toxins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU12820
Phenotypes of a mutant
- sporulation efficiency is reduced by four orders of magnitude PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- UniProt: O34800
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Patrik Florek, Vladimir M Levdikov, Elena Blagova, Andrey A Lebedev, Rostislav Škrabana, Stanislava Resetárová, Pamela Pavelcíková, Imrich Barak, Anthony J Wilkinson
The structure and interactions of SpoIISA and SpoIISB, a toxin-antitoxin system in Bacillus subtilis.
J Biol Chem: 2011, 286(8);6808-19
[PubMed:21147767]
[WorldCat.org]
[DOI]
(I p)
Patrik Florek, Katarína Muchová, Pamela Pavelcíková, Imrich Barák
Expression of functional Bacillus SpoIISAB toxin-antitoxin modules in Escherichia coli.
FEMS Microbiol Lett: 2008, 278(2);177-84
[PubMed:18096016]
[WorldCat.org]
[DOI]
(P p)
E Adler, I Barák, P Stragier
Bacillus subtilis locus encoding a killer protein and its antidote.
J Bacteriol: 2001, 183(12);3574-81
[PubMed:11371520]
[WorldCat.org]
[DOI]
(P p)
