KhtT

• Description: K+/H+ antiporter for K+ efflux
  
  

Gene name	yhaT
Synonyms
Essential	no
Product	K+/H+ antiporter for K+ efflux
Function	potassium ion efflux
MW, pI	18 kDa, 4.892
Gene length, protein length	495 bp, 165 aa
Immediate neighbours	yhaU, yhaS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU09860

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

transporters/ other, metal ion homeostasis (K, Na, Ca, Mg), membrane proteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: YhaT-YhaU PubMed

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: O07535

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Makoto Fujisawa, Masahiro Ito, Terry A Krulwich
Three two-component transporters with channel-like properties have monovalent cation/proton antiport activity.
Proc Natl Acad Sci U S A: 2007, 104(33);13289-94
[PubMed:17679694] [WorldCat.org] [DOI] (P p)

Makoto Fujisawa, Yuko Wada, Masahiro Ito
Modulation of the K+ efflux activity of Bacillus subtilis YhaU by YhaT and the C-terminal region of YhaS.
FEMS Microbiol Lett: 2004, 231(2);211-7
[PubMed:14987767] [WorldCat.org] [DOI] (P p)