Difference between revisions of "SqhC"

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= Categories containing this gene/protein =
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{{SubtiWiki category|[[sporulation proteins]]}},
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{{SubtiWiki category|[[resistance against oxidative and electrophile stress]]}}
 
=The protein=
 
=The protein=
  

Revision as of 20:16, 30 November 2010

  • Description: squalene-hopene cyclase, biosynthesis of sporulenes, protection of the spore against oxidative stress PubMed

Gene name sqhC
Synonyms
Essential no
Product squalene-hopene cyclase
Function biosynthesis of sporulenes
MW, pI 71 kDa, 7.633
Gene length, protein length 1896 bp, 632 aa
Immediate neighbours dhaS, sodF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SqhC context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU19320

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

Categories containing this gene/protein

sporulation proteins, resistance against oxidative and electrophile stress

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Squalene = hop-22(29)-ene (according to Swiss-Prot) production of sporulenes, polycyclic terpenoid lipids PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: surrounds the forespores PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed during sporulation in the mother cell PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

T Bosak, R M Losick, A Pearson
A polycyclic terpenoid that alleviates oxidative stress.
Proc Natl Acad Sci U S A: 2008, 105(18);6725-9
[PubMed:18436644] [WorldCat.org] [DOI] (I p)