Difference between revisions of "LicR"

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* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P46321 P46321]
 
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P46321 P46321]
  
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU38600]
+
* '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU38600]
  
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.1.69 2.7.1.69]
 
* '''E.C. number:''' [http://www.expasy.org/enzyme/2.7.1.69 2.7.1.69]

Revision as of 02:57, 25 June 2009

  • Description: transcriptional activator of the licB-licC-licA-licH operon

Gene name licR
Synonyms celR
Essential no
Product transcriptional activator (PRD type)
Function regulation of lichenan utilization
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 73 kDa, 6.115
Gene length, protein length 1923 bp, 641 aa
Immediate neighbours licB, yxzF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
LicR context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU38600

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)
  • Protein family: transcriptional antiterminator bglG family (according to Swiss-Prot), Attention: this is wrong: LicR is a transcription activator, the similarity to the BglG family is limited to the PTS-regulation domains
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

S Tobisch, J Stülke, M Hecker
Regulation of the lic operon of Bacillus subtilis and characterization of potential phosphorylation sites of the LicR regulator protein by site-directed mutagenesis.
J Bacteriol: 1999, 181(16);4995-5003
[PubMed:10438772] [WorldCat.org] [DOI] (P p)

S Tobisch, P Glaser, S Krüger, M Hecker
Identification and characterization of a new beta-glucoside utilization system in Bacillus subtilis.
J Bacteriol: 1997, 179(2);496-506
[PubMed:8990303] [WorldCat.org] [DOI] (P p)