Difference between revisions of "RodZ"

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(Extended information on the protein)
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16910 rodZ]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU16910 rodZ]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/RodZ RodZ]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 4.679   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 23 kDa, 4.679   

Revision as of 08:21, 30 July 2013

  • Description: required for cell shape determination

Gene name rodZ
Synonyms ymfM
Essential may be essential PubMed
Product morphogenic protein
Function required for cell shape determination
Gene expression levels in SubtiExpress: rodZ
Interactions involving this protein in SubtInteract: RodZ
MW, pI 23 kDa, 4.679
Gene length, protein length 639 bp, 213 aa
Immediate neighbours ymfK/2, pgsA
Sequences Protein DNA DNA_with_flanks
Genetic context
YmfM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RodZ expression.png















Categories containing this gene/protein

cell shape, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU16910

Phenotypes of a mutant

  • may be essential PubMed
  • depletion results in the formation of shorter and rounder cells PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

  • overexpression results in growth inhibition in minimal medium (in the absence of Mg2+ ) PubMed
  • RodZ is destabilized in a mreB mutant PubMed

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Adriano Henriques, Lisbon, Portugal homepage

Your additional remarks

References

Katarína Muchová, Zuzana Chromiková, Imrich Barák
Control of Bacillus subtilis cell shape by RodZ.
Environ Microbiol: 2013, 15(12);3259-71
[PubMed:23879732] [WorldCat.org] [DOI] (I p)

Ethan C Garner, Remi Bernard, Wenqin Wang, Xiaowei Zhuang, David Z Rudner, Tim Mitchison
Coupled, circumferential motions of the cell wall synthesis machinery and MreB filaments in B. subtilis.
Science: 2011, 333(6039);222-5
[PubMed:21636745] [WorldCat.org] [DOI] (I p)

Julia Domínguez-Escobar, Arnaud Chastanet, Alvaro H Crevenna, Vincent Fromion, Roland Wedlich-Söldner, Rut Carballido-López
Processive movement of MreB-associated cell wall biosynthetic complexes in bacteria.
Science: 2011, 333(6039);225-8
[PubMed:21636744] [WorldCat.org] [DOI] (I p)

S Anisah Alyahya, Roger Alexander, Teresa Costa, Adriano O Henriques, Thierry Emonet, Christine Jacobs-Wagner
RodZ, a component of the bacterial core morphogenic apparatus.
Proc Natl Acad Sci U S A: 2009, 106(4);1239-44
[PubMed:19164570] [WorldCat.org] [DOI] (I p)