Difference between revisions of "YrvM"

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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrvN]]'', ''[[bsrA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yrvN]]'', ''[[bsrA]]''
 
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27540 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27540 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27540 Advanced_DNA]
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU27540 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU27540 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU27540 DNA_with_flanks]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:yrvM_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:yrvM_context.gif]]

Revision as of 10:52, 14 May 2013

  • Description: similar to E. coli enzyme that catalyzes ATP-dependent dehydration of N6-threonylcarbamoyladenosine (t6A) to form cyclic N6-threonylcarbamoyladenosine (ct6A)

Gene name yrvM
Synonyms
Essential no
Product N6-threonylcarbamoyladenosine cyclase
Function tRNA modification
Gene expression levels in SubtiExpress: yrvM
MW, pI 28 kDa, 8.187
Gene length, protein length 762 bp, 254 aa
Immediate neighbours yrvN, bsrA
Sequences Protein DNA DNA_with_flanks
Genetic context
YrvM context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YrvM expression.png















Categories containing this gene/protein

translation

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU27540

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • catalyzes ATP-dependent dehydration of N6-threonylcarbamoyladenosine (t6A) to form cyclic N6-threonylcarbamoyladenosine (ct6A) (ct6A recognizes the first adenine base of ANN codon at the ribosomal A site) PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Kenjyo Miyauchi, Satoshi Kimura, Tsutomu Suzuki
A cyclic form of N6-threonylcarbamoyladenosine as a widely distributed tRNA hypermodification.
Nat Chem Biol: 2013, 9(2);105-11
[PubMed:23242255] [WorldCat.org] [DOI] (I p)