Difference between revisions of "SbcC"

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|style="background:#ABCDEF;" align="center"|'''Function''' || DNA inter-strand cross-link repair
 
|style="background:#ABCDEF;" align="center"|'''Function''' || DNA inter-strand cross-link repair
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU10650 sbcC]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU10650 sbcC]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SbcC SbcC]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/SbcC SbcC]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sbcD]]'', ''[[hlpB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[sbcD]]'', ''[[hlpB]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12905&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU10650 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU10650 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU10650 Advanced_DNA]
 
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Revision as of 12:30, 13 May 2013

  • Description: DNA exonuclease

Gene name sbcC
Synonyms yirY
Essential no
Product DNA exonuclease
Function DNA inter-strand cross-link repair
Gene expression levels in SubtiExpress: sbcC
Interactions involving this protein in SubtInteract: SbcC
MW, pI 128 kDa, 5.294
Gene length, protein length 3390 bp, 1130 aa
Immediate neighbours sbcD, hlpB
Sequences Protein DNA Advanced_DNA
Genetic context
YirY context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SbcC expression.png















Categories containing this gene/protein

DNA repair/ recombination, genetic competence

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU10650

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: SbcC subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
    • GP894 (sbcCD::kan), available in Stülke lab
    • 1A898 ( sbcC::cat), PubMed, available at BGSC
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Peter Graumann, Freiburg University, Germany homepage

Your additional remarks

References

Reviews

Peter L Graumann, Tobias Knust
Dynamics of the bacterial SMC complex and SMC-like proteins involved in DNA repair.
Chromosome Res: 2009, 17(2);265-75
[PubMed:19308706] [WorldCat.org] [DOI] (I p)

Original publications

Additional publications: PubMed