Difference between revisions of "PbuG"
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|style="background:#ABCDEF;" align="center"|'''Function''' || hypoxanthine and guanine uptake | |style="background:#ABCDEF;" align="center"|'''Function''' || hypoxanthine and guanine uptake | ||
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− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU06370 pbuG] |
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/purines_salvage_pathways.html Purine salvage], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/purines_salvage_pathways.html Purine salvage], [http://subtiwiki.uni-goettingen.de/pathways/gene_regulation_nucleotides.html Nucleotides (regulation)]''' | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[guaA]]'', ''[[yebC]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[guaA]]'', ''[[yebC]]'' | ||
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− | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU06370 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU06370 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU06370 Advanced_DNA] |
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|colspan="2" | '''Genetic context''' <br/> [[Image:pbuG_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:pbuG_context.gif]] |
Revision as of 12:17, 13 May 2013
- Description: hypoxanthin/ guanine permease
Gene name | pbuG |
Synonyms | yebB |
Essential | no |
Product | hypoxanthin/ guanine permease |
Function | hypoxanthine and guanine uptake |
Gene expression levels in SubtiExpress: pbuG | |
Metabolic function and regulation of this protein in SubtiPathways: Purine salvage, Nucleotides (regulation) | |
MW, pI | 46 kDa, 8.808 |
Gene length, protein length | 1320 bp, 440 aa |
Immediate neighbours | guaA, yebC |
Sequences | Protein DNA Advanced_DNA |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
transporters/ other, biosynthesis/ acquisition of nucleotides, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06370
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s): PbuO
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: membrane PubMed
Database entries
- Structure: 2EEW (the pbuG riboswitch, U47c mutant, bound to hypoxanthine)
- UniProt: O34987
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: pbuG PubMed
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- PurR: transcription repression (molecular inducer: PRPP) PubMed
- G-box: transcription termination/ antitermination (riboswitch) PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References