Difference between revisions of "YcnK"
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of copper uptake | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of copper uptake | ||
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| + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU03960 ycnK] | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 21 kDa, 7.371 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 21 kDa, 7.371 | ||
Revision as of 15:08, 6 August 2012
| Gene name | ycnK |
| Synonyms | |
| Essential | no |
| Product | transcription repressor |
| Function | regulation of copper uptake |
| Gene expression levels in SubtiExpress: ycnK | |
| MW, pI | 21 kDa, 7.371 |
| Gene length, protein length | 570 bp, 190 aa |
| Immediate neighbours | ycnJ, ycnL |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), transcription factors and their control
This gene is a member of the following regulons
The YcnK regulon:
The gene
Basic information
- Locus tag: BSU03960
Phenotypes of a mutant
elevated expression of ycnJ under conditions of copper excess PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Protein family: DeoR family of transcription factors
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): copper acts as corepressor PubMed
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P94433
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: ycnK (according to DBTBS)
- Sigma factor:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Mohamed Marahiel, Marburg University, Germany homepage
Your additional remarks
References
Shashi Chillappagari, Marcus Miethke, Hein Trip, Oscar P Kuipers, Mohamed A Marahiel
Copper acquisition is mediated by YcnJ and regulated by YcnK and CsoR in Bacillus subtilis.
J Bacteriol: 2009, 191(7);2362-70
[PubMed:19168619]
[WorldCat.org]
[DOI]
(I p)
Mélanie A Hamon, Nicola R Stanley, Robert A Britton, Alan D Grossman, Beth A Lazazzera
Identification of AbrB-regulated genes involved in biofilm formation by Bacillus subtilis.
Mol Microbiol: 2004, 52(3);847-60
[PubMed:15101989]
[WorldCat.org]
[DOI]
(P p)
