Difference between revisions of "MhqR"
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− | * '''Description:''' MarR-family transcriptional repressor of ''[[azoR2]'', ''[[mhqA]'', ''[[mhqD]]-[[mhqE]]'' and ''[[mhqN]]-[[mhqO]]-[mhqP]]'' expression <br/><br/> | + | * '''Description:''' MarR-family transcriptional repressor of ''[[azoR2]'' , ''[[mhqA]'' , ''[[mhqD]]-[[mhqE]]'' and ''[[mhqN]]-[[mhqO]]-[mhqP]]'' expression <br/><br/> |
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Revision as of 16:02, 15 December 2011
- Description: MarR-family transcriptional repressor of [[azoR2] , [[mhqA] , mhqD-mhqE and mhqN-mhqO-[mhqP]] expression
Gene name | mhqR |
Synonyms | ykvE |
Essential | no |
Product | MarR-family transcriptional repressor |
Function | regulation of resistance to quinones and diamide |
MW, pI | 16 kDa, 6.42 |
Gene length, protein length | 435 bp, 145 aa |
Immediate neighbours | kinD, motB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
Categories containing this gene/protein
transcription factors and their control, resistance against oxidative and electrophile stress
This gene is a member of the following regulons
The MhqR regulon
The gene
Basic information
- Locus tag: BSU13670
Phenotypes of a mutant
- resistant to quinones and diamide
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31672
- KEGG entry: [2]
- E.C. number:
Additional information
- Binding site: tATCTcgaAtTCgAGATaaaa PubMed
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Stefanie Töwe, Montira Leelakriangsak, Kazuo Kobayashi, Nguyen Van Duy, Michael Hecker, Peter Zuber, Haike Antelmann
The MarR-type repressor MhqR (YkvE) regulates multiple dioxygenases/glyoxalases and an azoreductase which confer resistance to 2-methylhydroquinone and catechol in Bacillus subtilis.
Mol Microbiol: 2007, 66(1);40-54
[PubMed:17725564]
[WorldCat.org]
[DOI]
(P p)