Difference between revisions of "FrlM"

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m (moved YurM to FrlM over redirect: 21347729)
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|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
 
|style="background:#ABCDEF;" align="center"|'''Gene name'''
|''yurM''
+
|''frlM''
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''frlM''
+
|style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yurM''
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 900 bp, 300 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 900 bp, 300 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yurL]]'', ''[[yurN]]''
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[frlD]]'', ''[[frlN]]''
 
|-
 
|-
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15248&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
 
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB15248&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:''' [[YurJ]]-([[YurM]]-[[YurN]])-[[YurO]] {{PubMed|10092453}}
+
* '''[[Interactions]]:''' [[YurJ]]-([[FrlM]]-[[FrlN]])-[[FrlO]] {{PubMed|10092453}}
  
 
* '''Localization:''' cell membrane {{PubMed|10092453}}
 
* '''Localization:''' cell membrane {{PubMed|10092453}}
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=Expression and regulation=
 
=Expression and regulation=
* '''Operon:''' ''[[yurR]]-[[yurQ]]-[[yurP]]-[[yurO]]-[[yurN]]-[[yurM]]-[[yurL]]'' {{PubMed|12823818}}
+
* '''Operon:'''  
 +
** ''[[yurR]]-[[yurQ]]-[[frlB]]-[[frlO]]-[[frlN]]-[[frlM]]-[[frlD]]'' {{PubMed|12823818}}
 +
** ''[[frlB]]-[[frlO]]-[[frlN]]-[[frlM]]-[[frlD]]'' {{PubMed|21347729}}
  
 
* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
** repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
+
**'' [[frlB]]'': repressed during growth in the presence of branched chain amino acids ([[CodY]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
 +
** ''[[frlB]]'': induced in the presence of fructosamine ([[FrlR]]) {{PubMed|21347729}}
  
 
* '''Regulatory mechanism:'''   
 
* '''Regulatory mechanism:'''   
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
+
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed1], [http://www.ncbi.nlm.nih.gov/sites/entrez/18083814 PubMed2]
 +
** [[FrlR]]: transcription repression {{PubMed|21347729}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
  
<pubmed>12618455,10092453,,12823818, </pubmed>
+
<pubmed>12618455,10092453, 21347729,12823818, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:03, 27 February 2011

Gene name frlM
Synonyms yurM
Essential no
Product aminosugar ABC transporter (permease)
Function uptake of sugar amines
Metabolic function and regulation of this protein in SubtiPathways:
Alternative nitrogen sources
MW, pI 34 kDa, 7.114
Gene length, protein length 900 bp, 300 aa
Immediate neighbours frlD, frlN
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YurM context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

ABC transporters, utilization of specific carbon sources, utilization of nitrogen sources other than amino acids, membrane proteins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU32580

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: MalFG subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • frlB: repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • frlB: induced in the presence of fructosamine (FrlR) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References