Difference between revisions of "YxdM"

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(Expression and regulation)
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* '''[[Sigma factor]]:'''  
 
* '''[[Sigma factor]]:'''  
  
* '''Regulation:'''  
+
* '''Regulation:'''
 +
** induced by a cationic antimicrobial peptide, LL-37 ([[YxdJ]])  {{PubMed| 21078927}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  

Revision as of 18:00, 17 November 2010

Gene name yxdM
Synonyms
Essential no
Product ABC transporter (permease)
Function export of toxic peptides
MW, pI 70 kDa, 9.272
Gene length, protein length 1866 bp, 622 aa
Immediate neighbours yxeA, yxdL
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YxdM context.gif
This image was kindly provided by SubtiList





The gene

Basic information

  • Locus tag: BSU39630

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ABC-4 integral membrane protein family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Anna Staroń, Dora Elisabeth Finkeisen, Thorsten Mascher
Peptide antibiotic sensing and detoxification modules of Bacillus subtilis.
Antimicrob Agents Chemother: 2011, 55(2);515-25
[PubMed:21078927] [WorldCat.org] [DOI] (I p)

Pascale Joseph, Annick Guiseppi, Alexei Sorokin, François Denizot
Characterization of the Bacillus subtilis YxdJ response regulator as the inducer of expression for the cognate ABC transporter YxdLM.
Microbiology (Reading): 2004, 150(Pt 8);2609-2617
[PubMed:15289557] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)