Difference between revisions of "RbsB"

From SubtiWiki
Jump to: navigation, search
Line 89: Line 89:
  
 
=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[rbsR]]-[[rbsK]]-[[rbsD]]-[[rbsA]]-[[rbsC]]-[[rbsB]]'' {{PubMed|7921236}}
  
* '''Operon:''' ''[[rbsR]]-[[rbsK]]-[[rbsD]]-[[rbsA]]-[[rbsC]]-[[rbsB]]''
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|7511775}}
 
 
* '''[[Sigma factor]]:''' [[SigA]]
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 +
** repressed by glucose ([[CcpA]]) {{PubMed|7921236}}
 
** expressed upon transition into the stationary phase ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed]
 
** expressed upon transition into the stationary phase ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed]
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[CcpA]]: transcription repression {{PubMed|7921236}}
 
** [[AbrB]]:  transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed]
 
** [[AbrB]]:  transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/7592460 PubMed]
  
Line 122: Line 123:
 
=References=
 
=References=
  
<pubmed>10092453,16872404,,7592460,18957862 7921236, </pubmed>
+
<pubmed>10092453,16872404,7511775,7592460,18957862 7921236, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:12, 9 January 2010

Gene name rbsB
Synonyms
Essential no
Product ribose ABC transporter (binding protein)
Function ribose uptake
Metabolic function and regulation of this protein in SubtiPathways:
Sugar catabolism
MW, pI 32 kDa, 6.138
Gene length, protein length 915 bp, 305 aa
Immediate neighbours rbsC, ywsB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
RbsB context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU35960

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacterial solute-binding protein 2 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot), extracellular (signal peptide) PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by glucose (CcpA) PubMed
    • expressed upon transition into the stationary phase (AbrB) PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References