Difference between revisions of "GerAC"
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=Expression and regulation= | =Expression and regulation= | ||
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* '''Operon:''' ''[[gerAA]]-[[gerAB]]-[[gerAC]]'' {{PubMed|3110007}} | * '''Operon:''' ''[[gerAA]]-[[gerAB]]-[[gerAC]]'' {{PubMed|3110007}} | ||
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* '''Regulation:''' | * '''Regulation:''' | ||
− | ** expressed during sporulation in the forespore ([[SigF]], [[SigG]]) {{PubMed|16497325,15699190}} | + | ** expressed during sporulation in the forespore ([[SigF]], [[SigG]], [[SpoVT]]) {{PubMed|16497325,15699190,8755877}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
+ | ** [[SpoVT]]: transcription repression {{PubMed|8755877}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
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=References= | =References= | ||
− | <pubmed>16740944,3110007,17573930,12670969,2110996,15774895,16497325,16352818, </pubmed> | + | <pubmed>16740944,3110007,17573930,12670969,2110996,15774895,16497325,16352818, 8755877</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 16:49, 28 December 2009
- Description: nutrient receptor, germination response to L-alanine
Gene name | gerAC |
Synonyms | |
Essential | no |
Product | nutrient receptor |
Function | germination response to L-alanine |
MW, pI | 42 kDa, 7.302 |
Gene length, protein length | 1119 bp, 373 aa |
Immediate neighbours | gerAB, liaR |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU33070
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: gerABKC lipoprotein family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P07870
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Venkata Ramana Vepachedu, Peter Setlow
Analysis of interactions between nutrient germinant receptors and SpoVA proteins of Bacillus subtilis spores.
FEMS Microbiol Lett: 2007, 274(1);42-7
[PubMed:17573930]
[WorldCat.org]
[DOI]
(P p)
Krzysztof Hinc, Krzysztofa Nagórska, Adam Iwanicki, Grzegorz Wegrzyn, Simone J Séror, Michal Obuchowski
Expression of genes coding for GerA and GerK spore germination receptors is dependent on the protein phosphatase PrpE.
J Bacteriol: 2006, 188(12);4373-83
[PubMed:16740944]
[WorldCat.org]
[DOI]
(P p)
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
Swaroopa Atluri, Katerina Ragkousi, Donna E Cortezzo, Peter Setlow
Cooperativity between different nutrient receptors in germination of spores of Bacillus subtilis and reduction of this cooperativity by alterations in the GerB receptor.
J Bacteriol: 2006, 188(1);28-36
[PubMed:16352818]
[WorldCat.org]
[DOI]
(P p)
Takao Igarashi, Peter Setlow
Interaction between individual protein components of the GerA and GerB nutrient receptors that trigger germination of Bacillus subtilis spores.
J Bacteriol: 2005, 187(7);2513-8
[PubMed:15774895]
[WorldCat.org]
[DOI]
(P p)
Rosa-Martha Cabrera-Martinez, Federico Tovar-Rojo, Venkata Ramana Vepachedu, Peter Setlow
Effects of overexpression of nutrient receptors on germination of spores of Bacillus subtilis.
J Bacteriol: 2003, 185(8);2457-64
[PubMed:12670969]
[WorldCat.org]
[DOI]
(P p)
I Bagyan, J Hobot, S Cutting
A compartmentalized regulator of developmental gene expression in Bacillus subtilis.
J Bacteriol: 1996, 178(15);4500-7
[PubMed:8755877]
[WorldCat.org]
[DOI]
(P p)
I M Feavers, J Foulkes, B Setlow, D Sun, W Nicholson, P Setlow, A Moir
The regulation of transcription of the gerA spore germination operon of Bacillus subtilis.
Mol Microbiol: 1990, 4(2);275-82
[PubMed:2110996]
[WorldCat.org]
[DOI]
(P p)
A R Zuberi, A Moir, I M Feavers
The nucleotide sequence and gene organization of the gerA spore germination operon of Bacillus subtilis 168.
Gene: 1987, 51(1);1-11
[PubMed:3110007]
[WorldCat.org]
[DOI]
(P p)