Difference between revisions of "Rex"

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(Biological materials)
(Extended information on the protein)
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* '''Cofactor(s):'''
 
* '''Cofactor(s):'''
  
* '''Effectors of protein activity:''' NADH (indication of low oxygen concentration) releases Rex from DNA [http://www.ncbi.nlm.nih.gov/sites/entrez/18485070 PubMed]
+
* '''Effectors of protein activity:''' NADH (indication of low oxygen concentration) releases Rex from DNA [http://www.ncbi.nlm.nih.gov/sites/entrez/18485070 PubMed], Rex has a very highh affinity for NADH
  
 
* '''Interactions:'''
 
* '''Interactions:'''

Revision as of 19:44, 6 May 2010

  • Description: transcriptional repressor of anaerobically expressed genes involved in anaerobic respiration and fermentation

Gene name rex
Synonyms ydiH
Essential no
Product transcriptional repressor
Function regulation of fermentation and anaerobic respiration
Metabolic function and regulation of this protein in SubtiPathways:
Central C-metabolism
MW, pI 23 kDa, 6.772
Gene length, protein length 645 bp, 215 aa
Immediate neighbours ydiG, tatAY
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YdiH context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU05970

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: transcriptional regulatory rex family (according to Swiss-Prot)
  • Paralogous protein(s):

Genes/ operons controlled by Rex

alsS-alsD, cydA-cydB-cydC-cydD, ldh-lctP, ywcJ PubMed

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: NADH (indication of low oxygen concentration) releases Rex from DNA PubMed, Rex has a very highh affinity for NADH
  • Interactions:
  • Localization: cytoplasm (according to Swiss-Prot)

Database entries

  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant: LUW292 (erm), GP834 (erm), both available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Claes von Wachenfeldt, Lund University, Sweden Homepage

Your additional remarks

References