Difference between revisions of "IlvC"

From SubtiWiki
Jump to: navigation, search
Line 18: Line 18:
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1026 bp, 342 aa  
 
|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1026 bp, 342 aa  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' ||  
+
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[leuA]]'', ''[[ilvH]]''
 
|-
 
|-
 
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/ilvC_nucleotide.txt    Gene sequence      (+200bp)  ]'''  
 
|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/ilvC_nucleotide.txt    Gene sequence      (+200bp)  ]'''  

Revision as of 16:40, 20 February 2009

  • Description: write here

Gene name ilvC
Synonyms
Essential no
Product ketol-acid reductoisomerase (acetohydroxy-acid isomeroreductase) (EC 1.1.1.86)
Function isoleucine synthesis
MW, pI 37 kDa, 5.37
Gene length, protein length 1026 bp, 342 aa
Immediate neighbours leuA, ilvH
Gene sequence (+200bp) Protein sequence
Genetic context
IlvC context.gif



The gene

Basic information

  • Coordinates:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • Swiss prot entry:
  • KEGG entry:
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed in the absence of branched-chain amino acids (BCAA), expression is stimulated in the presence of glucose PubMed
  • Regulatory mechanism: glucose regulation: CcpA PubMed, repression by BCAA: tRNA-controlled RNA switch (T-box) that mediates termination/antitermination, transcription repression by CodY
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed