Difference between revisions of "ComGE"

From SubtiWiki
Jump to: navigation, search
Line 39: Line 39:
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
<br/><br/><br/><br/>
 
<br/><br/><br/><br/>
 
 
 
 
<br/><br/>
 
<br/><br/>
  
Line 81: Line 77:
 
* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
+
* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
Line 92: Line 88:
 
** [[ComGB]]-[[ComGE]] {{PubMed|15083159}}  
 
** [[ComGB]]-[[ComGE]] {{PubMed|15083159}}  
 
** [[ComC]]-[[ComGE]] {{PubMed|9723928}}
 
** [[ComC]]-[[ComGE]] {{PubMed|9723928}}
 +
** [[ComGD]]-[[ComGE]] {{PubMed|24164455}}
 +
** [[ComGE]]-[[ComGG]] {{PubMed|24164455}}
  
 
* '''[[Localization]]:''' cell surface [http://www.ncbi.nlm.nih.gov/pubmed/9723928 PubMed]
 
* '''[[Localization]]:''' cell surface [http://www.ncbi.nlm.nih.gov/pubmed/9723928 PubMed]
Line 113: Line 111:
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comGE_2556921_2557268_-1 comGE] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=comGE_2556921_2557268_-1 comGE] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] {{PubMed|2507524}}
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|2507524}}
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
Line 145: Line 143:
 
<pubmed> 15083159 </pubmed>
 
<pubmed> 15083159 </pubmed>
 
==Original publications==
 
==Original publications==
<pubmed>9422590,9723928,11814663,2507524,12107147 8196543 </pubmed>
+
<pubmed>9422590,9723928,11814663,2507524,12107147 8196543 24164455</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:14, 16 March 2014

  • Description: DNA transport machinery, minor pseudopilin

Gene name comGE
Synonyms
Essential no
Product minor pseudopilin
Function genetic competence, DNA uptake
Gene expression levels in SubtiExpress: comGE
Interactions involving this protein in SubtInteract: ComGE
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 13 kDa, 5.238
Gene length, protein length 345 bp, 115 aa
Immediate neighbours comGF, comGD
Sequences Protein DNA DNA_with_flanks
Genetic context
ComGE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComGE expression.png















Categories containing this gene/protein

genetic competence

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU24690

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Inês Chen, David Dubnau
DNA uptake during bacterial transformation.
Nat Rev Microbiol: 2004, 2(3);241-9
[PubMed:15083159] [WorldCat.org] [DOI] (P p)

Original publications

Jessica M Mann, Valerie J Carabetta, Ileana M Cristea, David Dubnau
Complex formation and processing of the minor transformation pilins of Bacillus subtilis.
Mol Microbiol: 2013, 90(6);1201-15
[PubMed:24164455] [WorldCat.org] [DOI] (I p)

Ulrike Mäder, Georg Homuth, Christian Scharf, Knut Büttner, Rüdiger Bode, Michael Hecker
Transcriptome and proteome analysis of Bacillus subtilis gene expression modulated by amino acid availability.
J Bacteriol: 2002, 184(15);4288-95
[PubMed:12107147] [WorldCat.org] [DOI] (P p)

Hanne Jarmer, Randy Berka, Steen Knudsen, Hans H Saxild
Transcriptome analysis documents induced competence of Bacillus subtilis during nitrogen limiting conditions.
FEMS Microbiol Lett: 2002, 206(2);197-200
[PubMed:11814663] [WorldCat.org] [DOI] (P p)

Y S Chung, F Breidt, D Dubnau
Cell surface localization and processing of the ComG proteins, required for DNA binding during transformation of Bacillus subtilis.
Mol Microbiol: 1998, 29(3);905-13
[PubMed:9723928] [WorldCat.org] [DOI] (P p)

Y S Chung, D Dubnau
All seven comG open reading frames are required for DNA binding during transformation of competent Bacillus subtilis.
J Bacteriol: 1998, 180(1);41-5
[PubMed:9422590] [WorldCat.org] [DOI] (P p)

D van Sinderen, A ten Berge, B J Hayema, L Hamoen, G Venema
Molecular cloning and sequence of comK, a gene required for genetic competence in Bacillus subtilis.
Mol Microbiol: 1994, 11(4);695-703
[PubMed:8196543] [WorldCat.org] [DOI] (P p)

M Albano, R Breitling, D A Dubnau
Nucleotide sequence and genetic organization of the Bacillus subtilis comG operon.
J Bacteriol: 1989, 171(10);5386-404
[PubMed:2507524] [WorldCat.org] [DOI] (P p)