Difference between revisions of "SigA"
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigA_2600214_2601329_-1 sigA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=sigA_2600214_2601329_-1 sigA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
** ''[[yqxD]]'': [[SigA]] {{PubMed|3298998}}, [[SigH]] {{PubMed|3127379}} | ** ''[[yqxD]]'': [[SigA]] {{PubMed|3298998}}, [[SigH]] {{PubMed|3127379}} | ||
** ''[[sigA]]'': [[SigD]] {{PubMed|3919021}} | ** ''[[sigA]]'': [[SigD]] {{PubMed|3919021}} | ||
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<pubmed> 22210308 </pubmed> | <pubmed> 22210308 </pubmed> | ||
==Original publications== | ==Original publications== | ||
| − | + | <pubmed> 12486038,10556308,8107087, 14762002,7918363,8071196,7630711,9185571,9287022, 14679239, 14976210 19735077, 2997585,9658000,3127379 10438769,11535782,7599136, 9144176 19680289 20525796 22333917,20935043,20817769 23875654 </pubmed> | |
| − | <pubmed> 12486038,10556308,8107087, 14762002,7918363,8071196,7630711,9185571,9287022, 14679239, 14976210 19735077, 2997585,9658000,3127379 10438769,11535782,7599136, 9144176 19680289 20525796</pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:04, 25 July 2013
- Description: RNA polymerase major sigma factor SigA
| Gene name | sigA |
| Synonyms | rpoD, crsA |
| Essential | yes PubMed |
| Product | RNA polymerase major sigma factor SigA |
| Function | transcription |
| Gene expression levels in SubtiExpress: sigA | |
| Interactions involving this protein in SubtInteract: SigA | |
| MW, pI | 42 kDa, 4.634 |
| Gene length, protein length | 1113 bp, 371 aa |
| Immediate neighbours | cccA, dnaG |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
transcription, sigma factors and their control, essential genes, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25200
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: sigma-70 factor family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P06224
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
- An antisense RNA is predicted for sigA PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Charles Moran, Emory University, NC, USA homepage
Your additional remarks
References
Reviews
Lakshminarayan M Iyer, L Aravind
Insights from the architecture of the bacterial transcription apparatus.
J Struct Biol: 2012, 179(3);299-319
[PubMed:22210308]
[WorldCat.org]
[DOI]
(I p)
Original publications
