Difference between revisions of "YqgP"

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|style="background:#ABCDEF;" align="center"|'''Function''' || cell division or sugar metabolism
 
|style="background:#ABCDEF;" align="center"|'''Function''' || cell division or sugar metabolism
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU24870 yqgP]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU24870 yqgP]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 56 kDa, 5.507   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 56 kDa, 5.507   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqgQ]]'', ''[[yqgO]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yqgQ]]'', ''[[yqgO]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14418&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU24870 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU24870 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU24870 Advanced_DNA]
 
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Revision as of 13:18, 13 May 2013

  • Description: intramembrane protease

Gene name yqgP
Synonyms glpG, gluP
Essential no
Product intramembrane protease
Function cell division or sugar metabolism
Gene expression levels in SubtiExpress: yqgP
MW, pI 56 kDa, 5.507
Gene length, protein length 1521 bp, 507 aa
Immediate neighbours yqgQ, yqgO
Sequences Protein DNA Advanced_DNA
Genetic context
YqgP context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YqgP expression.png















Categories containing this gene/protein

proteolysis, membrane proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU24870

Phenotypes of a mutant

filamentous phenotype PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Cleaves type-1 transmembrane domains using a catalytic dyad composed of serine and histidine that are contributed by different transmembrane domains (according to Swiss-Prot)
  • Protein family: peptidase S54 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Philip Rather
Role of rhomboid proteases in bacteria.
Biochim Biophys Acta: 2013, 1828(12);2849-54
[PubMed:23518036] [WorldCat.org] [DOI] (P p)

Original publications

Padmapriya Sampathkumar, Michelle W Mak, Sarah J Fischer-Witholt, Emmanuel Guigard, Cyril M Kay, M Joanne Lemieux
Oligomeric state study of prokaryotic rhomboid proteases.
Biochim Biophys Acta: 2012, 1818(12);3090-7
[PubMed:22921757] [WorldCat.org] [DOI] (P p)

Sinisa Urban
Making the cut: central roles of intramembrane proteolysis in pathogenic microorganisms.
Nat Rev Microbiol: 2009, 7(6);411-23
[PubMed:19421188] [WorldCat.org] [DOI] (I p)

Lili R Mesak, Felix M Mesak, Michael K Dahl
Expression of a novel gene, gluP, is essential for normal Bacillus subtilis cell division and contributes to glucose export.
BMC Microbiol: 2004, 4;13
[PubMed:15050034] [WorldCat.org] [DOI] (I e)