Difference between revisions of "ComGA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]]
 
|style="background:#ABCDEF;" align="center"|'''Function''' || [[genetic competence]]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU24730 comGA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU24730 comGA]
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComGA ComGA]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/ComGA ComGA]
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comGB]]'', ''[[corA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[comGB]]'', ''[[corA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14404&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU24730 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU24730 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU24730 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:comGA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:comGA_context.gif]]

Revision as of 13:18, 13 May 2013

  • Description: late competence protein, traffic ATPase, binds and transports transforming DNA

Gene name comGA
Synonyms
Essential no
Product traffic ATPase
Function genetic competence
Gene expression levels in SubtiExpress: comGA
Interactions involving this protein in SubtInteract: ComGA
Metabolic function and regulation of this protein in SubtiPathways:
Protein secretion
MW, pI 40 kDa, 8.893
Gene length, protein length 1068 bp, 356 aa
Immediate neighbours comGB, corA
Sequences Protein DNA Advanced_DNA
Genetic context
ComGA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
ComGA expression.png
























Categories containing this gene/protein

genetic competence, membrane proteins, phosphoproteins

This gene is a member of the following regulons

ComK regulon

The gene

Basic information

  • Locus tag: BSU24730

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds and transports transforming DNA
  • Protein family: GSP E family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
    • phosphorylated on Arg-28, Arg-71- and Arg-330 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed by casamino acids PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Inês Chen, David Dubnau
DNA uptake during bacterial transformation.
Nat Rev Microbiol: 2004, 2(3);241-9
[PubMed:15083159] [WorldCat.org] [DOI] (P p)

Original publications