Difference between revisions of "SpmA"

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|style="background:#ABCDEF;" align="center"|'''Function''' || germination
 
|style="background:#ABCDEF;" align="center"|'''Function''' || germination
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU23180 spmA]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU23180 spmA]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 21 kDa, 10.031   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 21 kDa, 10.031   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spmB]]'', ''[[dacB]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spmB]]'', ''[[dacB]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14250&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU23180 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU23180 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU23180 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:spmA_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:spmA_context.gif]]

Revision as of 13:11, 13 May 2013

  • Description: spore maturation protein (spore core dehydratation)

Gene name spmA
Synonyms ypuJ
Essential no
Product spore maturation protein (spore core dehydratation)
Function germination
Gene expression levels in SubtiExpress: spmA
MW, pI 21 kDa, 10.031
Gene length, protein length 588 bp, 196 aa
Immediate neighbours spmB, dacB
Sequences Protein DNA Advanced_DNA
Genetic context
SpmA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpmA expression.png
























Categories containing this gene/protein

sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

  • Locus tag: BSU23180

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed early during sporulation in the mother cell (SigE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190] [WorldCat.org] [DOI] (P p)

D L Popham, B Illades-Aguiar, P Setlow
The Bacillus subtilis dacB gene, encoding penicillin-binding protein 5*, is part of a three-gene operon required for proper spore cortex synthesis and spore core dehydration.
J Bacteriol: 1995, 177(16);4721-9
[PubMed:7642500] [WorldCat.org] [DOI] (P p)

E B Simpson, T W Hancock, C E Buchanan
Transcriptional control of dacB, which encodes a major sporulation-specific penicillin-binding protein.
J Bacteriol: 1994, 176(24);7767-9
[PubMed:7528199] [WorldCat.org] [DOI] (P p)